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Homerun Resources Inc. (TSXV: HMR,OTC:HMRFF) (OTCQB: HMRFF) (‘Homerun’ or the ‘Company’) is proud to announce the successful first commercial installation of its proprietary energy management system, ‘The Hub,’ on a Risen battery energy storage system (BESS) at a customer site, marking a key commercialization milestone for the Company’s AI-driven energy solutions business.

The Hub is Homerun Energy’s advanced AI-enabled Energy Management System (EMS), built to orchestrate batteries and other flexible assets in real time to maximize revenue, reduce operating costs, and protect asset life. By connecting directly to the Risen BESS, The Hub now controls live charging and discharging at the customer’s site based on market signals, grid conditions, and on-site constraints, demonstrating full field functionality on a commercial battery platform.

‘This first commercial installation of The Hub on a Risen battery provides the validation investors have been waiting for,’ said Dr Luca Sorbello, CEO, Homerun Energy ‘We have moved from development to live operations, proving that our AI-enabled control system can unlock more value from storage assets while supporting a cleaner, more reliable grid.’

Learn more about the installation through this informative video: https://youtu.be/zwc_T0sPCVE

AI is central to the intelligence behind The Hub. By continuously analysing real-time data, from grid conditions and market prices to on-site consumption and battery health, The Hub’s AI models predict optimal dispatch strategies before they’re needed. This allows the system to automatically maximize revenue opportunities, reduce operating costs, and protect the battery from unnecessary wear. As The Hub learns from each installation, its algorithms become even more accurate, enabling smarter, faster, and more reliable control across an entire fleet of distributed energy assets.

The inaugural deployment enables:

  • Intelligent dispatch of the battery to capture price arbitrage, peak shaving, and grid-support services
  • Real-time monitoring and analytics, giving asset owners full visibility into performance and health
  • Configurable control strategies, allowing operators to adapt quickly to evolving tariffs, regulations, and market opportunities
  • Scalable architecture, built to manage fleets of storage assets across multiple sites

As renewable generation continues to grow, battery storage and intelligent control systems are becoming critical to balancing supply and demand. With The Hub now operating on a live battery installation, Homerun Energy is positioned to support developers, asset owners, and utilities looking to maximize the value of their storage portfolios.

‘Storage is only as smart as the software that controls it,’ added Luca Sorbello ‘The Hub was built from the ground up for flexibility and scale, so this first installation is just the beginning.’

Learn more at www.homerunenergy.com

About Homerun

Homerun Resources Inc. (TSXV: HMR,OTC:HMRFF) is building the silica-powered backbone of the energy transition across four focused verticals: Silica, Solar, Energy Storage, and Energy Solutions. Anchored by a unique high-purity low-iron silica resource in Bahia, Brazil, Homerun transforms raw silica into essential products and technologies that accelerate clean power adoption and deliver durable shareholder value.

  • ⁠Silica: Secure supply and processing of high-purity low-iron silica for mission-critical applications, enabling premium solar glass and advanced energy materials.
  • Solar: Development of Latin America’s first dedicated 1,000 tonne per day high-efficiency solar glass plant and the commercialization of antimony-free solar glass designed for next-generation photovoltaic performance.
  • Energy Storage: Advancement of long-duration, silica-based thermal storage systems and related technologies to decarbonize industrial heat and unlock grid flexibility.
  • ⁠Energy Solutions: AI-enabled energy management, control systems, and turnkey electrification solutions that reduce costs and optimize renewable generation for commercial and industrial customers.

With disciplined execution, strategic partnerships, and an unwavering commitment to best-in-class ESG practices, Homerun is focused on converting milestones into markets-creating a scalable, vertically integrated platform for clean energy manufacturing in the Americas.

On behalf of the Board of Directors of
Homerun Resources Inc.

‘Brian Leeners’

Brian Leeners, CEO & Director
brianleeners@gmail.com / +1 604-862-4184 (WhatsApp)

Tyler Muir, Investor Relations
info@homerunresources.com / +1 306-690-8886 (WhatsApp)

FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE

The information contained herein contains ‘forward-looking statements’ within the meaning of applicable securities legislation. Forward-looking statements relate to information that is based on assumptions of management, forecasts of future results, and estimates of amounts not yet determinable. Any statements that express predictions, expectations, beliefs, plans, projections, objectives, assumptions or future events or performance are not statements of historical fact and may be ‘forward-looking statements’.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

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To view the source version of this press release, please visit https://www.newsfilecorp.com/release/276016

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For years, rare earths have been discussed mostly in times of crisis — a supply scare here, a geopolitical flare there. This year, the strategic minerals are again taking center stage as China reasserts control over the sector.

The latest round of rare earths policy shifts has put new attention on how producers outside China are positioning themselves. For MP Materials (NYSE:MP), 2025 has been less about responding to market turbulence and more about testing what a viable, strategically resilient rare earths supply chain could look like beyond China’s dominance.

“We’ve been talking about these issues for many, many years,” CFO Ryan Corbett said during a fireside chat at the Benchmark Week conference in Marina del Rey, California.

“But the export controls in April put everything in stark relief.” The result, he told the audience, has been a level of public and government attention he has “never seen before.”

And the attention is coming at a pivotal moment for the US-based company.

This year marked five years since MP went public, an anniversary the team celebrated by ringing the bell at the New York Stock Exchange, as well as the culmination of several major announcements aimed at strengthening rare earths production, processing and magnet making outside of China.

The long road from mine to magnet

Corbett is the first to admit that the broader conversation around rare earths often oversimplifies the challenge. Headlines usually focus on mining or magnets, but the real bottlenecks, he stressed, live in the middle.

“You don’t magically take NdPr oxide and turn it into a magnet in a magnet factory,” he said. The process includes converting oxide to metal, metal to alloy flake, flake to powder, then pressing, sintering, slicing and grinding. Each step requires specific infrastructure, technical expertise and — perhaps most critically — experience.

Corbett sees this gap clearly in the wake of announcements from companies claiming to have plans for large-scale magnet facilities. “We see all these announcements — ‘We’re going to do a 10,000 ton magnet plant.’ They’ve never made metal before,” he said. “Good luck. It takes time. It takes investment. It takes R&D.”

When MP listed publicly five years ago, it was still producing only rare earths concentrate. The company told investors it would revisit magnet-making discussions around 2025.

Geopolitical urgency pushed MP to accelerate that timeline, leading to the company’s fully integrated US facility in Fort Worth, where metal, alloy and finished magnets are now all made domestically.

“It is critical that we master all of them at scale,” Corbett said. Without that know-how, any new facility will be vulnerable to single-point failures, the same dynamic that has left the industry heavily reliant on China.

Where the real rare earths bottleneck lies

When asked what truly slows down western rare earths supply chain development, Corbett didn’t point to mining. Instead, he pointed to refining, a stage China has dominated for decades.

“China doesn’t have 99 percent of the upstream reserves,” he noted. “They have the refining capacity and capability.”

That distinction is shaping MP’s next major step: a new world-scale refining facility in Saudi Arabia, built in partnership with Maaden and backed by the US Department of Defense (DoD).

The project is designed to process feedstocks from around the world, including materials that are too small, too short-lived or too geographically constrained to justify their own refineries.

Crucially, the new plant is being built with capital from the US government, not MP. “We didn’t want to be putting more capital at risk overseas while we’re fulfilling promises in the US,” Corbett said.

He added that the government wanted the facility built, and MP brought the technical and operational capability; the equity investment from the DoD bridged the gap.

The structure is unusual. According to Corbett, this is the first time since World War II that the DoD has taken an equity stake in a private enterprise. But he argued that the situation demands it.

“From a supply chain and national security perspective, we are that far behind.”

A price floor that reshapes incentives

The DoD’s involvement isn’t limited to the Saudi facility.

This past summer, the department also struck a landmark agreement with MP, establishing a price floor for NdPr oxide, the high-value rare earths ingredient inside permanent magnets.

The deal is “absolutely transformational,” Corbett said.

Rare earths prices have historically been highly vulnerable to sudden moves from China, a fact that has long posed an existential risk to western refiners. “What good is it to invest billions of dollars if the second you turn your refinery on, prices go from US$170 to US$45?” questioned Corbett.

The agreement is structured to avoid distorting the downstream market. MP still sells oxide at market prices; the government covers the difference only when prices fall below the negotiated threshold.

“It doesn’t impact the pricing of our magnets at all,” Corbett explained. “That was really important to us.”

If prices soar — something Corbett says he would welcome — MP would pay the government.

“I hope five years from now I’m being accosted by investors for taking this deal, because prices are so high we’re cutting checks back to the government,” he said.

Apple, recycling and the next phase

Also over the summer, MP announced another milestone — a major partnership with Apple (NASDAQ:AAPL) to source 100 percent recycled rare earth materials for the tech giant’s devices.

Recycling is often framed as a threat to miners. Corbett argues the opposite.

“It’s still a game of scale and expertise in refining,” he said. “It’s just a different feedstock.”

In many ways, recycled magnets are easier to process than raw ore. The challenge is achieving sufficient volume and consistency, something MP believes Mountain Pass is uniquely positioned to enable.

“Integration matters,” Corbett said. By blending recycled materials with the mine’s large, steady feedstock, MP can smooth out the variability inherent in end-of-life magnets.

A new playbook for national resources?

Taken together, MP’s 2025 announcements point toward a broader shift in how western governments approach critical minerals supply chains moving forward. Heavy government involvement through frameworks like equity stakes, price floors and international partnerships may represent a new template.

“This administration is approaching it with the mentality that it’s going to take real dollars to make this happen,” Corbett said. And if its investments pay off, he argued, they could help rebuild an industrial base the US hasn’t had in decades as MP positions itself to offer the full value chain, from mining and refining to producing finished magnets.

“Once the flywheel gets going,” Corbett said, “You’re onto something.”

Securities Disclosure: I, Georgia Williams, hold no direct investment interest in any company mentioned in this article.

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Bert Dohmen, founder and CEO of Dohmen Capital Research, discusses precious metals.

He believes gold’s fundamentals support ‘much higher prices’ for a number of years, and sees silver doing even better as the US faces down the specter of potential deflation.

Securities Disclosure: I, Charlotte McLeod, hold no direct investment interest in any company mentioned in this article.

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Homerun Resources Inc. (TSXV: HMR,OTC:HMRFF) (OTCQB: HMRFF) (‘Homerun’ or the ‘Company’) is pleased to announce that it has received TSXV conditional approval for its previously announced financing, originally announced on June 16, 2025, with an arm’s length institutional investor, Sorbie Bornholm LP (the ‘Investor’) in connection with a proposed financing for CDN$6,000,000.00 (the ‘Offering’) at a price of $1.00 per unit (‘Unit’).

The Offering will consist of the issuance of 6,000,000 Units. Each Unit shall be comprised of one (1) common share (‘Shares‘) of the Company and one (1) common share purchase warrant (‘Warrants‘). The proceeds from the Offering will be used to advance the Company’s vertically integrated silica to solar and energy storage business, supporting business development and scaling of revenues and for general working capital purposes.

Brian Leeners, CEO of Homerun stated, ‘We are thrilled to welcome this particular Institutional Investor as they have chosen Homerun to be their inaugural investment with a company trading on the TSX Venture Exchange. Their innovative investment model provides capital over 24 months keeping our team focused on the execution of our plans and deliverables. We have confidence that this financing based on its unique model, will provide capital premiums to the original financing amount over that 24-month period as we continue to de-risk our business and transition into a high-growth, revenue-generating Company with exceptional long-term potential.’

Sorbie Bornholm Managing Director Whitney Kofford commented, ‘Sorbie is proud to announce this new investment in Homerun Resources and to provide Homerun with flexible, growth-linked capital over the next two years through our unique Sharing Agreement. The global energy transition requires bold thinking and the ability to execute on transformative ideas. Homerun’s integrated strategy for high-purity silica and advanced energy solutions is a prime example of just that – innovation meeting opportunity. We applaud Homerun’s consistent track record of hard work and determination, and we look forward to supporting the Company over the longer-term throughout their growth trajectory.’

Pursuant to the terms and conditions of a Sharing Agreement between the parties, the following structure and sequence will take effect under the Offering:

  • The Investor will deposit CDN$6,000,000 into a third-party escrow account.
  • The Company will issue the 6,000,000 Shares into escrow and the Warrants will be issued to Sorbie on each monthly settlement date.
  • Over a 24-month period, the cash and Shares will be released monthly based on the Company’s market price at each release date.
  • The Investor will immediately receive upon closing 1,500,000 Warrants exercisable at CDN$1.18 for three (3) years.
  • The Investor will also receive up to 4,500,000 additional Warrants, issued monthly over 24 months, priced at a 20% premium to the 5-day VWAP at the time of each issuance and exercisable for three (3) years from issuance.
  • The Company will pay the Investor a corporate finance fee of 360,000 Shares and a due-diligence deposit of 100,000 Shares, both subject to the same escrow and release schedule.
  • The Warrants will also include an equity blocker provision that prohibits the Investor from exercising any portion of the Warrants if such exercise would result in the holder owning more than 9.99% of the Company’s outstanding Shares.

The Company intends to rely on the listed issuer financing exemption under Part 5A of National Instrument 45-106 – Prospectus Exemptions, as amended by Coordinated Blanket Order 45-935 – Exemptions from Certain Conditions of the Listed Issuer Financing Exemption, for the Offering, and the Shares and Warrants will not be subject to restrictions on resale. There will be an offering document related to the Offering that will be available under the Company’s profile at www.sedarplus.ca and at www.homerunresources.com. Prospective investors should read this offering document before making an investment decision. Closing of the Offering is subject to several conditions, including receipt of all necessary corporate and regulatory approvals, including the TSXV.

The Offering is expected to close on or about November 30, 2025, or such other date as the Company may determine, and is subject to certain conditions including, but not limited to, the receipt of all necessary regulatory and other approvals, including the final approval of the TSX Venture Exchange. There are no finder’s fees payable to any parties under the Offering.

About Homerun (www.homerunresources.com)

Homerun is building the silica-powered backbone of the energy transition across four focused verticals: Silica, Solar, Energy Storage, and Energy Solutions. Anchored by a unique high-purity low-iron silica resource in Bahia, Brazil, Homerun transforms raw silica into essential products and technologies that accelerate clean power adoption and deliver durable shareholder value.

  • ⁠Silica: Secure supply and processing of high-purity low-iron silica for mission-critical applications, enabling premium solar glass and advanced energy materials.
  • Solar: Development of Latin America’s first dedicated 1,000 tonne per day high-efficiency solar glass plant and the commercialization of antimony-free solar glass designed for next-generation photovoltaic performance.
  • Energy Storage: Advancement of long-duration, silica-based thermal storage systems and related technologies to decarbonize industrial heat and unlock grid flexibility.
  • Energy Solutions: AI-enabled energy management, control systems, and turnkey electrification solutions that reduce costs and optimize renewable generation for commercial and industrial customers.

With disciplined execution, strategic partnerships, and an unwavering commitment to best-in-class ESG practices, Homerun is focused on converting milestones into markets-creating a scalable, vertically integrated platform for clean energy manufacturing in the Americas.

On behalf of the Board of Directors of Homerun Resources Inc.:

‘Brian Leeners’

Brian Leeners, CEO & Director
brianleeners@gmail.com / +1 604-862-4184 (WhatsApp)

Tyler Muir, Investor Relations
info@homerunresources.com / +1 306-690-8886 (WhatsApp)

FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE

The information contained herein contains ‘forward-looking statements’ within the meaning of applicable securities legislation. Forward-looking statements relate to information that is based on assumptions of management, forecasts of future results, and estimates of amounts not yet determinable. Any statements that express predictions, expectations, beliefs, plans, projections, objectives, assumptions or future events or performance are not statements of historical fact and may be ‘forward-looking statements’.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

This news release does not constitute an offer to sell or a solicitation of an offer to buy any securities in the United States. The securities have not been and will not be registered under the United States Securities Act of 1933, as amended (the ‘U.S. Securities Act’) or any state securities laws and may not be offered or sold within the United States or to U.S. Persons unless registered under the U.S. Securities Act and applicable state securities laws or an exemption from such registration is available.

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To view the source version of this press release, please visit https://www.newsfilecorp.com/release/275995

News Provided by Newsfile via QuoteMedia

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A Florida man was arrested after an FBI investigation linked him to multiple extremist group chats on the encrypted messaging app Signal, where agents claim he used aliases to share disturbing graphic messages, detailed instructions for explosives and violent neo-Nazi propaganda.

Lucas Alexander Temple, 20, is facing federal charges for distribution of information regarding the manufacturing or use of explosives and possession of an unregistered short-barreled shotgun, according to court documents.

According to criminal complaints, Temple shared a hand-drawn diagram of a homemade detonator, linked to YouTube videos describing how to synthesize dynamite and construct blasting caps, and posted a 122-page extremist manual filled with White supremacist rhetoric. 

Investigators said the chats also included graphic discussions promoting rape, torture and murder, including the killing of non-White children.

Screenshots of messages allegedly sent by Temple’s aliases included phrases like, ‘How long would it take to rape a femboy to death?’ and discussions about sexually assaulting men.

Temple’s online aliases were linked to his true identity through personal details shared in chats — including his age, job at a grocery store and a family museum visit — and were verified with state records and security footage, according to the complaint.

While executing a search warrant at Temple’s home on Thursday, FBI agents found neo-Nazi propaganda, a book related to Columbine High School shooters Dylan Klebold and Eric Harris and a Springfield Model 67 Series E shotgun with a barrel shorter than 18 inches.

The barrel was allegedly sawed off and found in a separate area by investigators.

ATF records confirmed Temple was not registered to have the weapon.

Agents also found a handwritten note that said, ‘Plans: Wear body cams for livestream. Notify friends of livestream. Put flags on car. Play music on car speakers during operation. Place motion-activated bombs in doorways (for cops).’

During his initial court appearance, Magistrate Judge Amanda Arnold Sansone ordered that he remain detained pending trial, finding he posed a serious danger to others.

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This press release is issued pursuant to the requirements of National Instrument 62-103 – The Early Warning System and Related Take-Over Bid and Insider Reporting Issues

In accordance with the requirements of Section 3.1 of National Instrument 62-103 – The Early Warning System and Related Take-Over Bid and Insider Reporting Issues, Matthew J. Mason announces that, in connection with the closing of the Technology Licensing Agreement (the ‘Agreement’) with Stallion Uranium Corp. (TSXV: STUD,OTC:STLNF) (OTCQB: STLNF) (FSE: B76) (the ‘Issuer’), he has acquired 3,750,000 Common Shares of the Issuer at a deemed price of $0.12 per Common Share.

Immediately before the closing of the Agreement: (i) Mr. Mason held an aggregate of 20,825,000 Common Shares, representing approximately 17% of the Issuer’s issued and outstanding Common Shares on an undiluted basis; and (ii) assuming the exercise in full of all of the convertible securities of the Issuer held by Mr. Mason, being 15,137,500 Warrants to purchase an additional 15,137,500 Common Shares, Mr. Mason would have held an aggregate of 35,962,500 Common Shares, representing approximately 29% of the Issuer’s issued and outstanding Common Shares on a partially diluted basis.

Immediately after the closing of the Agreement: (i) Mr. Mason held an aggregate of 24,575,000 Common Shares, representing approximately 19% of the Issuer’s issued and outstanding Common Shares on an undiluted basis; and (ii) assuming the exercise in full of all of the convertible securities held by Mr. Mason, being 15,137,500 Warrants to purchase an additional 15,137,500 Common Shares, Mr. Mason would hold a total of 39,712,500 Common Shares, representing approximately 30% of the Issuer’s issued and outstanding Common Shares on a partially diluted basis.

Mr. Mason acquired such Common Shares for investment purposes and may, from time to time, acquire additional securities of the Issuer or dispose of such securities as he may deem appropriate, on the basis of his assessment of market conditions and in compliance with applicable securities regulatory requirements. A copy of the early warning report filed by Mr. Mason may be obtained on the Issuer’s SEDAR+ profile at www.sedarplus.ca.

For more information, please contact the Acquiror at 925 West Georgia Street, Vancouver, British Columbia V6C 3L2.

NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR FOR DISSEMINATION IN THE UNITED STATES

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/275960

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CopAur Minerals Inc. (TSXV: CPAU) (‘CopAur’ or the ‘Company’) announces that pursuant to the press release on November 24th, 2025, by Omega Pacific Resources Ltd (CSE: OMGA) (‘Omega’), that CopAur and Omega (the ‘Parties’) have completed an amendment of the Williams Property (the ‘Property’) Option/Joint Venture Agreement (the ‘Option Agreement’) to accelerate Omega’s acquisition of a 100% interest in the Property.

On February 29, 2024, the Parties entered into an Option Agreement (see CopAur’s March 1st, 2024, press release) whereby Omega could earn up to a 100% interest in the Williams Property. On April 24th, 2024, CopAur announced the receipt of $1 million in cash and 3 million Omega shares from Omega, which along with agreed upon exploration expenditures and other considerations, allowed Omega to earn a 51% interest in the Williams property. On November 12th, 2024, Omega exercised its option to acquire a 51% interest in the property.

On November 20th, 2025, the Parties entered into a second amendment to the Option Agreement whereby Omega has the option to acquire the remaining 49% interest in the Williams Property from CopAur on or before December 4th, 2025, by issuing to CopAur, 3.3 million common shares in the capital of Omega.

CopAur is confident that the Williams Property, located in BC’s re-emerging Toodoggone District and the Golden Horseshoe, which is widely regarded as a tier-one exploration region, holds tremendous, untapped mineral value as confirmed during Omega’s 2024 drill program that returned values of 1.69 g/t Au over 104 metres and 2.16 g/t Au. over 96.9 metres. Omega has the requisite skill set to further develop this property, and this agreement allows CopAur to concentrate our efforts on our Nevada properties. We look forward to following developments at the Williams Property as a significant shareholder of Omega,’ commented Andrew Neale, CEO.

About CopAur
CopAur is a mine development company focused on projects within the emerging, mineral-rich gold mining regions of Nevada. The Company is backed by a dynamic and experienced team of resource professionals advancing its projects in Nevada with the flagship project being Kinsley Mountain Gold Project, a Carlin-style project located in the Kinsley Mountains in Eastern Nevada, approximately 80 km SSW of West Wendover.

ON BEHALF OF THE BOARD OF COPAUR MINERALS INC.
Andew Neale, Chief Executive Officer

For more information, please contact:

Andrew Neale, Chief Executive Officer
Email: ir@copaur.com

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release.

Forward-Looking Information

This news release contains forward-looking statements. All such statements involve substantial known and unknown risks, uncertainties and other factors which may cause the actual results to vary from those expressed or implied by such forward-looking statements. Forward-looking statements involve significant risks and uncertainties, they should not be read as guarantees of future performance or results and they will not necessarily be accurate indications of whether or not such results will be achieved. Actual results could differ materially from those anticipated due to a number of factors and risks. Although the forward-looking statements contained in this news release are based upon what management of the Company believes are reasonable assumptions on the date of this news release, the Company cannot assure investors that actual results will be consistent with these forward-looking statements. The forward-looking statements contained in this press release are made as of the date hereof and the Company disclaims any intention or obligation to update or revised any forward-looking statements whether as a result of new information, future events or otherwise, except as required under applicable securities regulations.


Source

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Artificial intelligence (AI) is fundamentally reshaping biotechnology and healthcare, unlocking the secrets hidden within complex biological data.

Machine learning in genomics and proteomics is transforming how diseases are detected, monitored and treated. Central to this revolution are innovative platforms tackling some of medicine’s toughest challenges, integrating AI with molecular biology to accelerate drug development, improve diagnostics and personalize patient care.

This wave of AI-driven biotechnology not only promises to improve lives by addressing unmet medical needs but also offers investors a rare opportunity to support scalable, data-rich solutions, setting the stage for potential disruptive growth in healthcare.

AI unlocking biological complexity: From data to decision

The challenge of interpreting vast amounts of biological data, which has long slowed progress in disease detection and drug discovery, is precisely where AI offers a valuable solution.

For example, liquid biopsy, which analyzes DNA fragments circulating in the blood, exemplifies AI’s power to break new ground. Unlike invasive tissue biopsies, liquid biopsy offers a minimally invasive window into the body’s molecular makeup.

However, signals in blood can be extremely subtle, especially for chronic diseases like liver conditions, which have eluded detection with older methods. Transformer-based AI models adapted to biological data can analyze millions of molecular interactions simultaneously, uncovering faint patterns and signatures that traditional methods miss, enabling early detection and personalized diagnostics that can dramatically improve outcomes.

Hepta, a liquid biopsy company developed by experts from Illumina (NASDAQ:ILMN) and GRAIL, Inc. (NASDAQ:GRAL), has created an AI platform that analyzes epigenetic patterns in circulating cell-free DNA.

The company recently came out of stealth mode with US$6.7 million in seed funding led by Felicis Ventures and Illumina Ventures, among others. Its technology is designed to replace invasive biopsies with simple blood draws, showing strong early clinical results for detecting liver disease.

CEO Hamed Amini described how Hepta’s platform is uniquely designed from the ground up to deliver a specialized approach that sets it apart from earlier AI tools used in cancer research, opening the door to new possibilities for broad applications.

“I think in the not-distant future, we’re going to be at a place where generating ample genomic data is truly not going to be a cost barrier anymore,” he said. “Once you get there, I envision a super comprehensive central assay that captures all this epigenetic signal from a blood sample (to determine patient eligibility for certain treatments). You can expand this to oncology and other chronic diseases down the line, hopefully.’

AI accelerates drug discovery and personalizes cancer care

AI is also drastically transforming cancer care by accelerating drug discovery and development, with the potential to revolutionize medicine, according to an editorial in the Lancet Oncology. Author Abhishek Mehta observes that many academic cancer centers are collaborating with private companies to use AI for optimizing drug development, trials and analytics.

For example, the cancer drug BBO-10203 was developed by researchers at Lawrence Livermore National Laboratory and Frederick National Laboratory for Cancer Research in collaboration with private biotech company BridgeBio Oncology Therapeutics. Developers used advanced computing and AI to go from conception to human trials in just six years. This is a stark improvement to the 10 to 15-year timeline of the traditional drug development process.

Other key innovators include Rakovina Therapeutics (TSXV:RKV), a Canadian biotech company, which is using its AI platforms, Deep-Docking and Enki, to help discover drugs that target the DNA damage repair process in cancer cells.

One of its main programs is a therapy that blocks a key protein that cancer cells need to survive. Rakovina has found promising candidates and is working with top cancer research centers to move these treatments toward human trials.

Recently, it has partnered with a biotech company specializing in advanced lipid nanoparticle technology designed with AI assistance to develop AI-discovered cancer therapies. The company has also expanded access for US investors through new trading eligibility.

Beyond optimizing drug candidates and delivery mechanisms, AI is also being deployed to develop targeted therapeutic strategies.

“The next improvement in human life and survival comes from the next platform shift, and we really believe that metabolism is that, and this trial would allow us to really open that door for people in their minds,” Parikh explained, adding that the complexity of metabolic function necessitates the need for machine learning. “There are no approaches around metabolism and cancer that can thrive and survive and be reproducible without leveraging machine learning.”

Personalized, data-driven healthcare’s expanding frontier

Looking ahead, AI is reshaping drug development pipelines, with techniques like DeepDR and SNF-CVAE expected to enhance drug discovery and repurposing, speeding up clinical timelines.

For investors, the economic implications of such efficiency gains are profound: faster approvals and lower development costs can significantly increase returns while reducing risk.

Not only will AI tools help pharmaceutical companies select promising candidates faster and design smarter trials, but industry insiders maintain that they can eventually help physicians personalize therapies to patient-specific profiles.

In Faeth’s case, its AI-driven MetabOS platform reduces the data related to cancer metabolism to a smaller, more tractable set of potential targets. Then, CRISPR gene-editing technology allows further experimental validation and refinement to identify the most promising therapeutic candidates with high precision.

“There’s a cohort of patients .. .that are really benefiting,” Parikh said of the DICE trial. “And so we’re going to figure out who those patients are, and then make sure physicians are getting those patients on it early so they can derive the maximum benefit.”

However, widespread adoption faces hurdles, including regulatory pathways and data quality standards; still, growing investor interest and strategic partnerships indicate strong momentum in overcoming these barriers. As Parikh said, “If the data … (are good), more capital will come.”

For example, Danish medical AI company Corti is increasingly finding traction by offering healthcare institutions “AI infrastructure” designed specifically for medical use cases

Governments are also investing heavily in AI for disease research, exemplified by the US$500 billion US Stargate Project, which includes funding allocated to AI-driven biomedical research and infrastructure development; and the UK’s £19 million PharosAI initiative supporting AI-powered cancer research and clinical innovation.

The bottom line

AI-driven platforms are on the frontline of healthcare innovation.

For investors with an eye toward the future, this is an opportunity to support transformative science while participating in a market with tremendous growth potential. This is not just about technology; it’s about changing how medicine is practiced and ultimately, how lives are improved and saved.

Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.

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Rep. Marjorie Taylor Greene’s surprise resignation from Congress stunned House Republicans and sets up an even tighter majority in the lower chamber that could foil major legislative priorities.

Whether it triggers a ripple effect of Republican lawmakers following her lead remains to be seen. Still, there are members of the House GOP who are frustrated by how events have unfolded in recent months, especially after House Speaker Mike Johnson, R-La., opted to keep the House in session for over 50 days during the government shutdown.

Rep. Mike Haridopolos, R-Fla., told Fox News Digital he’s ‘heard rumors’ of frustration among his colleagues but, from people he’s spoken with, ‘They’re committed to being here.’

‘This is an incredible honor to serve in the House of Representatives, and when you run for office, I think you should fill out your term,’ Haridopolos said.

‘This is what the American public wanted,’ he continued. ‘I mean, they affirmatively put Republicans in power. And the only frustration we’ve been through, at least my biggest frustration, is when the Democrats exercise their power to shut the government down for 43 days.’

Greene, in her resignation letter teeing up her departure from Congress Jan. 5, 2026, aired grievances about how little progress has been made on Capitol Hill since she became a lawmaker in 2021.

She also took aim at President Donald Trump, who she has for weeks been distancing herself from despite being a die-hard Trump loyalist for much of her legislative career, and at Johnson for his handling of the shutdown.

‘During the longest shutdown in our nation’s history, I raged against my own speaker and my own party for refusing to proactively work diligently to pass a plan to save American healthcare and protect Americans from outrageous overpriced and unaffordable health insurance policies,’ Greene said. ‘The House should have been in session working every day to fix this disaster, but instead America was forced fed disgusting political drama once again from both sides of the aisle.’

Rep. Blake Moore, R-Utah, the fifth highest-ranking House Republican, sought to quash any rumors of dissent among the ranks in a statement to Fox News Digital.

‘Speaker Johnson and the House Republican leadership team have made a diligent effort to listen to all members of the conference for input, policy ideas and concerns,’ he said. ‘As usual, the media is building a negative narrative, but our record of delivering for the American people with our majority this year speaks to our teamwork and unity.’

That majority is now headed for a tenuous situation with Greene’s retirement.

Though Republicans are expected to maintain a seat after former Rep. Mark Green, R-Tenn., retired, the special election to replace the late former Rep. Sylvester Turner, D-Texas, is expected to stay in Democratic control, effectively nullifying the results.

That means when Greene leaves, and if the results in Tennessee in December favor Republicans, Democrats are hoping for a miracle in the race. The results in Texas in late January favor Democrats, so the GOP would be left with effectively a two-vote majority.

Another lawmaker was tempted to exit the House for a different reason.

Rep. Don Bacon, R-Neb., was furious over the White House’s 28-point plan for Russia and Ukraine and told Fox News Digital that he found it ‘so appalling, so embarrassing.’

Bacon argued that the plan, which has broadly been viewed as giving Moscow much of what it wants and leaves Ukraine with little other than an end to the ongoing war, was ‘a recipe for Ukraine being abused for decades to come, and to be basically a vassal state under Russian control. And that was unacceptable.’

His preference is that if Ukraine is pushed to give up territory to Russia, it should be allowed to join the North Atlantic Treaty Organization at the very least.

He noted that he ran on a pro-Ukraine platform, and, for a moment, considered resigning, fast-tracking his planned retirement from Congress at the end of next year.

‘I was so frustrated, it went through my mind,’ Bacon said. ‘You know, I don’t want to be a part of this team, frankly, but I don’t — I knew it was wrong. It was short-lived.

‘I think people would be doing a disservice to a lot of people just to resign,’ he continued. ‘I frankly think you should only resign if you got, like, an illness, or your spouse has an illness, or you got a legal issue. You know, when you run, there’s a commitment.’

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President Donald Trump pardoned a pair of turkeys at the White House on Tuesday, going on to joke that former President Joe Biden’s turkey pardons last year were ‘null and void’ because he used an autopen.

Trump made the joke while carrying out the decades-long White House Thanksgiving tradition, this year pardoning ‘Gobble’ and ‘Waddle.’ The crowd laughed as Trump said he saved last year’s turkeys, ‘Peach’ and ‘Blossom’ from being carved up after the nullification of Biden’s pardons.

‘I wanted to make an important announcement. Because you remember last year, after a thorough and very rigorous investigation by [Attorney General] Pam Bondi and all of the people at Department of Justice, the FBI, the CIA, and the White House Counsel’s Office…I have determined that last year’s turkey pardons are totally invalid,’ Trump said.

‘Null and void,’ Trump said of the pardons. ‘The turkeys known as Peach and Blossom last year have been located, and they were on their way to be processed, in other words, to be killed. But I’ve stopped that journey, and I am officially pardoning them. And they will not be served for Thanksgiving dinner. We saved them in the nick of time.’

This year’s turkeys, ‘Waddle’ and ‘Gobble,’ are the largest turkeys ever to receive a presidential pardon, Trump said. Both of the birds weigh over 50 pounds.

A National Turkey Federation spokeswoman told reporters at the White House that after Waddle and Gobble are pardoned, they will move to North Carolina State University, where they will serve as ‘Turkey ambassadors for our industry.’

First lady Melania Trump held a poll on X to name this year’s turkeys, resulting in Waddle and Gobble.

Last year’s pardoned turkeys, the aforementioned Peach and Blossom, and the ones before them, ‘Liberty’ and ‘Bell,’ all came from Minnesota.

North Carolina, Indiana, Iowa, South Dakota, Ohio, California, Virginia and Missouri have all sent turkeys to the White House.

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